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Chunk #3 — INTRODUCTION

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Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans.
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et al. 2011; Splawski et al. 2002). Expanding genetic association studies to diverse populations has been of recent interest to many investigators in the field. To date there has been one GWAS published for ECG traits in African Americans on PR interval and one fine-mapping study for QT interval in African Americans (Avery et al. 2012; Smith et al. 2011). Missing from the current literature is a comprehensive study of multiple ECG traits that explain the generalizability or lack thereof across populations. Furthermore, to date there are no GWAS reported for heart rate in African Americans.