We calculated externalizing polygenic scores using estimates from a multivariate genomic analysis of externalizing behaviors/problems (which included alcohol problems, attention-deficit/hyperactivity disorder (ADHD), lifetime cannabis use, age of first sexual intercourse, number of sexual partners, general risk tolerance, and lifetime smoking initiation) with an effective sample size of ~1.5 million individuals of European ancestry, from the international Externalizing Consortium(Karlsson Linnér et al. in press). For a detailed description of the samples and phenotypes that went into the multivariate genomic modeling, please see Karlsson Linnér (in press) and its pre-registered analysis plan (https://osf.io/pmyq8/).
