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Chunk #24 — Results — Environmental Factors

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The structure of genetic and environmental risk factors for syndromal and subsyndromal common DSM-IV axis I and all axis II disorders.
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The factor loadings for the three environmental factors are presented in Table 4 and Figure 2 (which includes all paths with loadings ≥0.316). Four broad patterns of findings are noteworthy. First, two disorders are missing in Figure 2—eating disorders and specific phobia, which did not load appreciably on any of the three environmental factors. Second, the overall factor pattern does not resemble that seen for the genetic factors. The first factor includes nine of the 10 axis II disorders and reflects a common set of environmental experiences that predispose nonspecifically to all forms of personality disorders. Factor 1 can best be termed axis II personality disorders. Factor 2 loads primarily on axis I internalizing disorders, including most (but not all) of the anxiety disorders, major depression, dysthymia, and somatoform and eating disorders. Alcohol abuse or dependence also loads moderately on this factor, which nonetheless is probably most accurately identified as an axis I internalizing disorders factor. The third factor had substantial positive loadings on three of the classical externalizing disorders (antisocial personality disorder, conduct disorder, and drug abuse or dependence) and negative loadings on agoraphobia and panic disorder.