Chunk #18 — Methods — Proposed methods — The proposed efficient method

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An efficient genome-wide association test for multivariate phenotypes based on the Fisher combination function.

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Using the adapt function in the R package fCopulae [29], we obtained the following estimates: c1=3.9081,c2=0.0313,c3=0.1022,c4=−0.1378 and c5=0.0941; the maximum residual was less than 0.0001.