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Chunk #17 — MATERIALS AND METHODS — Signal Recording and Processing — EEG signal preprocessing.

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Cross-frequency phase-amplitude coupling in repetitive movements in patients with Parkinson's disease.
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3-s duration (−1 s to 2 s relative to the peripheral movement onset). To ensure equal treatment of the resting dataset, we randomly generated and inserted 150 fake markers into the original raw datasets, and the epoching information was saved based on these fake markers. For the fast tapping task, we only used every second movement onset marker to reduce the overlap between epochs. The number of recorded movement cycles varied between the different movement tasks, with the least number of repetitions performed in the pressing task. To obtain a comparable number of movement cycles across conditions, we randomly selected trials in resting, slow tapping, and fast tapping conditions, such that their numbers matched that derived from the pressing task. The average number of epochs was 106, and no significant differences (P > 0.05, before correction) were found between patients and controls or across conditions (as detailed in Supplemental Table S2).