The PDD has been used widely to study the stigma of serious mental illness and has been adapted to measure the stigma of AUDs and other SUDs. To our knowledge, this is the first study to systematically evaluate the factor structure of the PDD and the construct validity of the alcohol-adapted version. A one-factor model with adjustment for method effects offered the most parsimonious solution to modeling PAS. The labeled group had the strongest inverse relationship between PAS and social support as expected, yet the same was not true for analyses involving social network involvement. Measurement and theoretical insights can be derived from these findings.