Necessary inclusion criteria included the diagnosis of ASD or Pervasive Developmental Disorder not otherwise specified (PDD-nos) - both hereafter bundled and together referred to as ASD - as determined by an independent pediatric neurologist, psychiatrist, or psychologist at CHB or at one of several other Harvard teaching hospitals, specializing in childhood developmental disabilities, including ASD. Diagnoses relied upon DSM-IV [1] and/or ADOS [34-36] criteria aided by clinical history and expert team evaluation.