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Chunk #22 — MATERIALS AND METHODS — Support vector machines

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Classification and selection of biomarkers in genomic data using LASSO.
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As mentioned earlier, an advantage of this approach is that most of the gene effects are estimated to be exactly zero. The method can also identify the genes associated with each of the two classes. Genes whose coefficients are negative are associated with the class g = −1, while those with positive estimated coefficients are associated with g = 1.