number for the sample size is important for LDpred30.) Before each filtered file was cleared for subsequent meta-analyses, we also prepared and visually inspected a number of diagnostic plots, as described in Okbay et al. Our final analyses are limited to files whose diagnostic plots did not suggest any anomalies. Finally, we examined the genetic correlation between input files (estimated using the LDSC software package59) for each phenotype to make sure phenotype coding was in the same direction across 23andMe, UKB, and published studies. Supplementary Table 7 summarizes the number of SNPs dropped in each filtering step in the files that passed all diagnostic checks.
