Additionally, genes having cross-species hits acquired bonus scores (the "Cross" score in our algorithm, see Table 1), as cross-species evidence was regarded as an important factor in gene salience. Here, we used score to estimate the evidence of a gene, rather than using a quantitative measurement (e.g., significance level, see section Materials and methods). We proposed 10 weighting score matrices (Table 1). The corresponding ranking results are shown in Table 2.
