With the exception of AIAN and API men and women, among whom we observed steady increases in alcohol-induced deaths over the study period, trends were not consistent among other racial/ethnic groups (Table and Figure 1). For black women, the overall decrease from 2000 to 2016 reflected both a large decrease between 2000 and 2007 (APC, −5.9%; 95% CI, −8.2% to −3.6%) and a subsequent increase from 2007 to 2016 (APC, 3.1%; 95% CI, 1.5% to 4.8%). Similarly, whereas the overall trend among black men decreased from 2000 to 2016, the rate decreased substantially between 2000 and 2006 (APC, −6.2%; 95% CI, −7.5% to −4.9%), slowed between 2006 and 2012 (APC, −1.7%; 95% CI, −3.6% to 0.2%), and then increased from 2012 to 2016 (APC, 2.7%; 95% CI, 0.2% to 5.4%).