Here, we provide a description of the genome-wide data that were generated on the Add Health sibling pairs subsample. In particular, we focus on describing the targeted sample for genotyping, the quality control (QC) and quality assurance (QA) steps that were taken and how putative biological relationships were assessed. Using genome-wide data from known reference populations, we alsoshow the genetic ancestry of the Add Health sibling pairs subsample. We also explore the genetic heritability of body mass index (BMI) using the genome-wide data from the Add Health sibling pairs subsample. Finally, rather than conducting a traditional cross-sectional genome-wide association study (GWAS) of BMI, we opt to utilize the rich genome-wide information publicly available to conduct a weightedgenome-wide association study (GWAS) of longitudinal BMI while accounting for both family and ethnic variation. Funding for the genotyping of the sibling pairs subsample was provided by the National Institutes of Child Health and Human Development (R01 HD060726).
