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Chunk #29 — RESULTS — Genetic correlation analysis

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Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity.
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LD score regression based genetic correlations with a wide range of psychopathological and behavioral phenotypes with published GWAS results are shown in Supporting Information Figure S7. Significant effects were observed but failed to survive multiple testing correction (FDR or Bonferroni). Top effects included r G = –.35 (uncorrected p = .0094, FDR p > .10) between theta power and autism spectrum disorder, and r G = .55 (uncorrected p = .014, FDR p > .10) between beta power and generalized epilepsy. Also, a nominally significant genetic correlation between heart rate and alpha power was observed (r G = .22, p = .019).