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Chunk #32 — Materials and Methods — Database

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Potential Role of S-Palmitoylation in Cancer Stem Cells of Lung Adenocarcinoma.
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The RNA-seq results and clinical data for LUAD patients (n = 515) and normal samples (n = 59) was obtained from the LUAD dataset of the TCGA database.1 The GEO database2 is an open-access platform, providing gene expression results performed by microarray, including clinical data. The CPTAC is a database, designed for large-scale proteome and genome analysis. Protein expression analysis in this study used mass-spectrometry-based proteomic data from the CPTAC Confirmatory/Discovery cohorts. The HPA (Uhlén et al., 2015) is an open access knowledge resource, with the aim to map all the human proteins in cells, tissues and organs. The HPA consists of six separate parts, and the Tissue Atlas (Uhlén et al., 2005), Pathology Atlas (Uhlen et al., 2017), Cell Type Atlas and Cell Atlas (Thul et al., 2017) were used in this study.