Chunk #17 — Materials and Methods — Association mapping

Source

Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).

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Post hoc analyses were carried out to determine the effect of the two most significant SNPs on individual phenotypes; 3×3×6 repeated measures ANOVAs (SPSS 17.0) were conducted with genotype as the grouping factor and dose and time as the two within-subjects factors; age, sex, BMI, and the first two principal components from SmartPCA were included as covariates.