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Chunk #39 — Methods — Trait Ascertainment

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Identification of 15 genetic loci associated with risk of major depression in individuals of European descent.
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For the branched data sources 4 and 5, participants were first asked a screening question (4a or 5a), and if they answered affirmatively, were asked a specific follow-up question (4b or 5b). Cases were defined as positive responses to the follow-up question, and controls were the union of ‘no’ responses to either the screening or follow-up questions.