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Chunk #0 — GENOME-WIDE ASSOCIATION STUDIES AND ‘THE MISSING HERITABILITY'

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Synthetic associations in the context of genome-wide association scan signals.
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Numerous common human diseases and phenotypic traits are believed to arise from a combination of genetic and environmental factors. The unravelling of the genetic predisposition to complex traits is a major challenge, and it could lead to better prevention, diagnosis and treatment of disease.