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Chunk #103 — 8.0 Moving from GWAS-implicated Loci to Causal Variants

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Endophenotype best practices.
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yes

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Up to now we have focused primarily on recommendations for improving the discovery of new genes associated with endophenotypes, and therefore genes that are presumably important for clinical disorders. Let us assume now, contrary to available evidence, that we have been successful in discovering a variant. What next?