observed for ADH1C (alcohol dehydrogenase 1C) which produced a permuted value of p=0.015 in the combined sample. Considering the two samples separately, the most significant result was ADH1C in the EA sample (p=0.003) and POMC (proopiomelanocortin) in the AA sample (p = 0.0008). In the EA sample, p<0.1 was observed for PECR (peroxisomal trans-2-enoyl-coA reductase), ERC2 (ELKS/RAB6-interacting/CAST family member 2), ADH1C, NFKB1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 1), and ANKK1. In the AA sample, the 7 genes producing trend results (p<0.1) were: ADH5 (alcohol dehydrogenase 5), DKK2 (dickkopf homolog 2), PPP2R2B (protein phosphatase 2, subunit B, beta isoform), GABRR1 (gamma amino-butyric acid receptor, rho 1), CHRM2 (cholinergic receptor, muscarinic 2), ZNF699 (zinc finger protein, 699), and POMC.
