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Chunk #21 — Results — Linkage disequilibrium score regression (LDSC)

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Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa.
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p=1.6×10−3); free cholesterol in large HDL particles (rg =0.37, SE=0.12, p=2.2×10−3); and phospholipids in large HDL particles (rg =0.30, SE=0.11, p=6.7×10−3). In contrast, VLDL cholesterol phenotypes were negatively correlated with AN, albeit with nominal significance (i.e., uncorrected p<.05): e.g., total lipids in VLDL (rg =−0.30, SE=0.12, p=0.01); phospholipids in VLDL (rg =−0.33, SE=0.13, p=4.4×10−3); and LDL cholesterol (rg =−0.20, SE=0.08, p=0.011).