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Chunk #10 — Historical Perspectives — Comparative Studies on the Effects of Cannabis and Ethanol

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A review of the interactions between alcohol and the endocannabinoid system: implications for alcohol dependence and future directions for research.
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recall, but only acute ethanol impaired performance on a number recognition task (Heishman et al., 1997; Heishman et al., 1988). With regard to the cognitive effects of chronic ethanol and cannabis exposure, one study demonstrated significantly impaired learning in a Hebb-Williams maze and a punished moving belt test for rats that were chronically treated with either 6 g/kg ethanol or 10mg/kg THC for six months and allowed to recover for one month before training (Fehr et al., 1976). These studies suggest that although ethanol and cannabis have distinct subjective effects, these two drugs produce similar deficits in cognitive function after both acute and chronic administration.