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Chunk #25 — Methods — Genotyping, Quality Control, and Imputation

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Identification of 15 genetic loci associated with risk of major depression in individuals of European descent.
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For the X chromosome, we built separate haplotype graphs for the non-pseudoautosomal region and each pseudoautosomal region, and these regions were phased separately. We then imputed males and females together using Minimac2, as with the autosomes, treating males as homozygous pseudo-diploids for the non-pseudoautosomal region.