applied to the Drug Use Chart to delineate the probability of alcohol and cannabis use in relation to severity of overall substance use, taking into account 10 drug categories (alcohol, cannabis, crack/cocaine, opiates, amphetamines, sedatives, tobacco, hallucinogens, PCP, and inhalants; Kirisci, Vanyukov, Dunn, & Tarter, 2002). Item characteristic curves were derived to depict the probability of alcohol and cannabis use in relation to the person’s overall severity of substance use. Lastly, it was determined whether the sequential order of alcohol use and cannabis use on a probability scale mediates the association of TLI with AUD and CUD.