We selected samples per brain region using five common inclusion criteria: (1) RiboZero RNA-seq library preparation; (2) recent African ancestry; (3) TOPMed-imputed genotypes available; (4) adults (aged > 17 years); and (5) diagnosis of neurotypical control. This resulted in a total of 425 samples from 151 unique individuals across the caudate nucleus (n = 121, 50 female and 72 male), dentate gyrus (n = 47, 16 female and 32 male), DLPFC (n = 123, 48 female and 75 male) and hippocampus (n = 133, 53 female and 80 male). Participant details including age, sex and RNA integrity number are summarized in Table 1. Individual-level details are provided in Supplementary Data 11.
