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Chunk #20 — Association Studies — Meta-analysis of additional datasets — Schizophrenia

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Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder.
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The numbers of cases and controls for each of the samples we included in the meta-analysis are given in supplemental table 5. Details of the samples from the published GWAS studies of the International Schizophrenia Consortium(5), the Molecular Genetics of Schizophrenia (MGS) consortium(7), the SGENE plus consortium(6),and of Lencz and colleagues(20) are given in the primary GWAS publications. The SW3 sample had been genotyped using an Affymetrix 6 chip at the Broad Institute of MIT and was part of the same on-going patient collections as samples SW1 and SW2 from the ISC data set(21). Details of the samples used in the candidate gene study of ZNF804A based upon the Irish Case/Control Study of Schizophrenia (ICCSS) sample are also available in a primary manuscript(10). It should be noted that those samples do not overlap with any of the Irish samples provided by the Dublin group.