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Chunk #44 — Fig. 3

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Effects of the serotonin transporter gene, sensitivity of response to alcohol, and parental monitoring on risk for problem alcohol use.
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Interaction of SRE-5 × Parental Monitoring Predicting Drinks per YearA visual depiction of the moderated mediation effect (interaction only; i.e., the simple slopes of SRE-5 predicting drinks per year at low, moderate, and high levels of parental monitoring, controlling for 5-HTTLPR and drinks before SRE-5 assessment, sex, age at SRE-5 assessment, and body mass index). Using the PROCESS macro, the conditional indirect effect of 5-HTTLPR was significant at low and moderate levels of parental monitoring (effects denoted with an *), with higher SRE-5 scores associated with a greater number of drinks per year. Drinks per year was square root transformed. 5-HTTLPR, serotonin transporter-linked polymorphic region of the serotonin transporter gene (SLC6A4); SRE-5, Self-Rating of the Effects of Alcohol (first five drinking occasions; standardized person-mean imputation method [Lee et al., 2015]).