Chunk #29 — NICOTINE DEPENDENCE
Text
A recent GWAS for COPD also found association of rs1051730 with COPD.47 This association remained significant after adjusting for pack-years (P = 5.7 × 10−10). Although this finding suggests that this is a true association with COPD, the investigators acknowledged that the lack of further smoking variables makes it difficult to identify the full contribution of nicotine exposure on COPD.