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Chunk #29 — NICOTINE DEPENDENCE

Source
Genetics of addictions.
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A recent GWAS for COPD also found association of rs1051730 with COPD.47 This association remained significant after adjusting for pack-years (P = 5.7 × 10−10). Although this finding suggests that this is a true association with COPD, the investigators acknowledged that the lack of further smoking variables makes it difficult to identify the full contribution of nicotine exposure on COPD.