A total of 28 SNPs in 7 LD-independent loci had q<0.1 (Table 1). These include SNPs in two loci with prior support from both human and MO alcohol studies (the ryanodine receptor 3 (RYR3) gene, chr. 15q14, rs4780153, p=1.47×10−7, Figure 3B and the Krueppel-like factor 12 (KLF12) gene, chr. 13q22.1, rs117695261, p=6.63×10−8, Figure 3C). Four additional regions with suggestive signals are shown in Supplementary Figure S5B–E.
