In the Utah Obesity Study, marked weight reduction 2 years after gastric bypass induced regression of left ventricular hypertrophy and ventricular enlargement and improved biventricular systolic function. These occurred in parallel with improved left ventricular diastolic relaxation and tissue Doppler parameters that correlated with improved exercise capacity.21 Additionally, electrophysiological properties may change, with several studies demonstrating correction of abnormal QTc intervals, heart rate recovery, and autonomic tone.
