We included subjects recruited in two stages for studies of the genetics of methamphetamine dependence. For both stages, subjects were recruited at the Princess Mother National Institute on Drug Abuse Treatment (PMNIDAT; formerly Thanyarak Institute) located in Bangkok using similar ascertainment methods (with the main phenotyping assessment via the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA—Thai version)). Studies were approved by The Faculty of Medicine, Chulalongkorn University Institutional Review Board (Med Chula IRB), the Ethical Review Committee for Research in Human Subjects, Thailand Ministry of Public Health, the Research Committee, Thanyarak Institute on Drug Abuse; and the Yale Human Investigations Committee. Subject characteristics are shown in Table 1. All subjects provided voluntary written informed consent prior to their research participation and were compensated (500 baht, or roughly US$15), per institutional review board (IRB) approval.
