Although our MTG findings were found in association with prenatal exposure effects, others have noted MTG results in association with familial risk effects. In an fMRI study assessing BOLD response to Go/NoGo trials, Acheson et al., (2014 a,b) observed higher activations in the in the middle temporal gyrus (BA 39 and 19) in their family history positive group. However, family history positive alcohol naïve youth have been reported to show blunted BOLD response in MTG for happy faces in an fMRI study (Cservenka et al., 2014). Similarly, HR youth show diminished BOLD response in the middle temporal gyrus during performance of the theory of mind task (Eyes Task of Baron-Cohen), a task which requires identification of emotions based on pictures of eyes on a screen (Hill et al., 2007).
