ERO measures have been used as effective tools to understand brain mechanisms underlying alcoholism and its predisposition (for reviews, see Porjesz et al., 2005; Pandey et al., 2012; Rangaswamy and Porjesz, 2014; Kamarajan and Porjesz, 2015). Further, as reported in the combined analyses of ERP and ERO data, ERO measures yielded additional information than the traditional ERP measures to discriminate alcoholics from controls (e.g., Jones et al., 2006b) as well as high-risk from low-risk individuals (e.g., Rangaswamy et al., 2007).