In contrast to the abundant number of alcohol challenge studies in FHP men, substantially fewer studies have assessed the behavioral response to alcohol in FHP women, with early studies reporting inconsistent differences between FHP and FHN females (Lex et al., 1988, 1994; Savoie et al., 1988). Over the last decade, studies with larger sample sizes have been conducted in FHP women. For instance, Schuckit et al. (2000) reported that FHP males (n = 75) and FHP females (n = 38) showed decreased ratings of intoxication and less impairment on body sway following a single dose of alcohol compared to FHN males (n = 68). However, that study reported no significant differences between FHP females and FHN females and this was attributed to the small sample of FHN females (n = 11). A more recent study compared ratings of intoxication and body sway following a single dose of alcohol in 25 FHP and 25 FHN females (Eng et al., 2005). Despite this larger sample, FHP women only showed significantly lower intoxication ratings at a single time point. Even after drug use,
