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Chunk #20 — Results — Overlap of methylation QTLs and expression QTLs in the top Bipolar Disorder SNPs

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Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.
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Thus, we conclude that the enrichment of cerebellum mQTLs and that of eQTLs in the Bipolar Disorder data are independent features. The variants that are both eQTLs and mQTLs for the same proximal target transcript are not driving the observed enrichment. They should thus be considered separately in terms of biological functionality.