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Chunk #73 — Results — Detecting recombination events — Informative pedigrees

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A general approach for haplotype phasing across the full spectrum of relatedness.
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Figure 5 compares the gene flow (and hence recombination) inferred by Merlin and the recombination probabilities inferred by our method for 10 informative meioses between parent-child duos from the Val Borbera cohort on chromosome 10. This figure shows very good agreement between our estimated probabilities and the events inferred by Merlin. However, these examples highlight that Merlin does infer some rather implausible, sporadic events in some meioses (even after running Merlin's error detection).