results must be interpreted with caution. Here we related eQTLs in the lung to GWAS studies for asthma which is an airway disease but which is known to involve other tissue types including immune cells. The genetic control of gene expression is tissue specific. Regulatory variants for GSDMA identified in the lung may regulate a different gene(s) in another relevant tissue or cell-type for asthma. More functional work in multiple tissues and cell-types measuring gene expression with or without various stimuli will be required to confirm the causal asthma gene on 17q21.
