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Chunk #84 — Future Directions: Combining Stress and Alcohol Models and Assessment of Multigenerational Effects and Therapeutics — Multigenerational Effects

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Epigenetic mechanisms in alcohol- and adversity-induced developmental origins of neurobehavioral functioning.
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alterations in maternal behavior due to the fitness of the offspring or mating patterns of the male could explain the perpetuation of epigenetic marks across generations rather than germline transmission (Whitelaw, 2015). Future work is needed to parse apart the effects of prenatal and postnatal environment versus germline transmission in the perseverance of epigenetic marks between generations.