For all genotyped samples pooled together (n = 244), the PTSD-PRS has an AUC (area under the receiver operating characteristic curve) of 0.60 for PTSD diagnosis and a C-index of 0.58 for prediction of CAPS. Next, using the PRS values, participants are stratified into equal-sized quantiles. The odds ratio for PTSD diagnosis between the highest and lowest quartiles is 11.2 (95% CI = 5.4–23.1), and between highest and lowest deciles is 50.5 (95% CI = 15.9–160) (Fig. 2). Similarly, the difference in mean CAPS between the highest and lowest quartiles is 40.7 (95% CI = 0.9–80.5), and between highest and lowest deciles is 58.3 (95% CI = −12.5–129.1) (Fig. 2).
