All simulations concerned N = 2000 subjects and 20 standard normally distributed phenotypes (N∼(0,1)), unless stated otherwise. Simulated GVs (MAF = .5) explained 0 to 1% (with steps of .01) of the variance in either the latent factor, or in a specific phenotype (see below). All simulations were repeated Nsim = 2000 times. Simulations and analyses were conducted in R [31].
