Chunk #17 — Results — Mega-analysis — Influence of symptom dimensions on cortical thickness and surface area — Children:

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Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group.

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Pediatric OCD patients with ordering and symmetry symptoms (N=181) showed a higher surface area of the left cuneus (Cohen’s d 0.49; Supplementary Table S20 and Figure S14). None of the regions analyzed showed significant differences in cortical thickness or evidence of associations with the other symptom dimensions.