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Chunk #23 — Results — Publication Bias and Fail-safe Analyses

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Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians.
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The classic fail-safe analysis showed that for the allelic analysis about 10,386 assumed non-significant studies would be required to bring the P(Z) value to > 0.05; and for the dominant model about 10,120 non-significant studies would be required to bring the P(Z) value to > 0.05. These results further supported the strong associations detected in the meta-analysis.