In the past two years, we have built upon this foundation by expanding target–disease evidence data, adding pharmacovigilance, safety and tractability information, improving the scoring of evidence and prioritisation of targets, and enriching our disease ontology. We have incorporated a new drug index to include all parent molecules with known pharmacological action or disease indication. We have integrated novel data generated from Open Targets consortium informatics and experimental projects. These updates have been informed by our users and members of the Open Targets consortium. We have also expanded our training and outreach scope, providing tutorials and interactive sessions to help inform and support users.