paperKB
coga / coga-kb
Help
Sign in

Chunk #18 — BACKGROUND — First findings of ENIGMA‐OCD: Cortical thickness, surface area and subcortical volume

Source
An overview of the first 5 years of the ENIGMA obsessive-compulsive disorder working group: The power of worldwide collaboration.
Embedded
yes

Text

cortical connectivity profile and functions (Behrens et al., 2003). OCD‐related enlargement of the overall thalamus may therefore be driven by one or a few subnuclei. Which subnuclei drive this effect is currently unknown, although shape analysis has revealed increased surface area in anterior and pulvinar nuclei in adult OCD patients (Shaw et al., 2015). In future studies, we will employ the recently developed and validated algorithm from Iglesias et al. (2018) to segment the subnuclei of the thalamus and study which nuclei drive the effect.