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Chunk #34 — Discussion and concluding remarks — Clinical perspectives

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15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse.
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Further development of delta and kappa opioid drugs will join the growing body of studies addressing other targets, such as gamma-aminobutyric acid receptors and voltage-gated ion channels. These drugs will likely complete other non-pharmacological therapies, including transcranial magnetic stimulation or behavioral, cognitive therapies and group therapies considered very effective in long-term treatments (Addolorato et al., 2012; Volkow and Skolnick, 2012).