We also evaluated our associations for overlap with previously reported expression QTLs. We confirmed associations with a previously reported eQTL in LRAP (renamed ERAP2) [1], and also SNP regulation of RPS26 expression [2,8]. While previous reports document an overall transcript change [2,8,9], we identified the effects of the SNP to be localized to specific exons in the RPS26 transcript. This discrepancy is probably due to microarray platform differences. We also confirmed in our PBMC sample set several previously reported sQTLs established in HapMap cell lines, including sQTLs in ULK4, PARP2, C17orf57, and others [5].
