To investigate the spatiotemporal dynamics of the human brain transcriptome, we created a 15-period system spanning from embryonic development to late adulthood (Table 1; Supplementary Information 2.1). We sampled transient prenatal structures and immature and mature forms of 16 brain regions, including 11 NCX areas, from multiple specimens per period (Table 2; Supplementary Information 2.2; Supplementary Figs. 1-3; Supplementary Table 1). The 11 NCX areas are referred to hereafter collectively as the region NCX. We also genotyped donor's DNA using an Illumina 2.5 million SNP chip (Supplementary Fig. 4; Supplementary Table 2). Only brains from clinically unremarkable donors with no signs of large-scale genomic abnormalities were included in the study (N=57, including 39 with both hemispheres; age, 5.7 post-conceptual weeks to 82 years; sex, 31 males and 26 females; postmortem interval [PMI], 12.11±8.63 [mean±SD] hours; pH, 6.45±0.34 [mean±SD]).
