Chunk #25 — Methods — Simulation — Generating SNPs

Source

Dosage transmission disequilibrium test (dTDT) for linkage and association detection.

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yes

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We have considered three disease models: dominant, recessive and co-dominant. The combinations of the penetrances in these three models are designed as follows: dominant (f 11<f 12 = f 22), recessive (f 11 = f 12<f 22) and co-dominant (f 11<f 12 = ½ f 22).