no statistically significant effects of chronic free-choice alcohol drinking on gene expression in the striatum of C57BL/6By mice. The above rodent studies were conducted using ethanol injections or 24-hour free-choice drinking. Moreover, other than the study of Kerns et al. (2005) using i.p. ethanol injections, none of the above rodent studies reported data on limbic regions that are involved in mediating alcohol drinking.
