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Chunk #12 — Subjects and Methods — Laboratory Procedures — Subjective Response Assessments

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GABRA2 markers moderate the subjective effects of alcohol.
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Biphasic Alcohol Effects Scale (BAES) (Martin et al., 1993) is composed of 14 items measuring both stimulant and sedative effects of alcohol. Subjects rated the extent to which they experienced these feelings at the present time on a scale from 1 (not at all) to 9 (extremely). These measures were summed to yield two scales: (a) “Stimulant” effects, which are the sum of “elated, energized, excited, stimulated, talkative, up, and vigorous” effects, and (b) “Sedative” effects, which are the sum of “difficulty concentrating, down, heavy head, inactive, sedated, slow thoughts and sluggish” effects.