Approximately 70 strains were available for phenotyping, allowing improved power for QTL mapping and genetic correlation. BXD 1–42/TyJ strains were obtained from the Jackson Laboratory (Bar Harbor, ME, USA). Recent BXD RI lines (Peirce et al. 2004) were provided by Dr Lu Lu and Dr Robert W. Williams (University of Tennessee Health Science Center, Memphis, TN, USA).